Caroline, x10000 is a pretty big step in a single stage, more likely you would need to step up in 2 stages, and include filtering at each stage to keep out unwanted signals. So you need to know the frequency band of your signal that you are trying to measure. you should get a book on the design of opamp circuit designs to see how they work, but a real basic x100 circuit would look something like this attempt in ASCII ART... |\ in | \ ----1000---| - \ out | >-----x--------- ----| + / | | | / | | |/ | | | ------100000----- note: the 1000 is a 1K resistor and the 100000 is a 100K resistor. the gain is set by 100000/1000 which is 100, so if you stick two of these in series you get x10000 or there abouts. In a proper circuit you add other components like capacitors, power etc.. To make it filter capacitor(s) across the 100000 or from the left side of the 10000 to ground changes the gain at different frequencies. If you are only dealing with DC signals this is not so important and your circuit can be simpler. hope this gives you an idea where to start. I think this is the type of circuit used in my temperature controlled soldering iron, because the temperature sensor puts out a certain number of uV for every degree in temperature. I have an almost correct circuit diagram of that in the manual it came with if that'd be any use to you, let me know Mark figjams AT primus DOT com DOT au Caroline.Payne wrote in message news:3BF62928.F35A8365@durham.ac.uk... > Does anyone kow how to make an amplifier to multiply an input signal > from a thermocouple (of about 11 micro V) by 10,000 to be read in by an > oscilloscope? > Would really appreciate some help on this! > Thanks, Caroline